Peripheral arterial disease (PAD) describes a phenomenon in which circulation to the leg is diminished due to atherosclerosis, resulting in reduced blood flow and often causing pain that can be limiting to those who experience it.
The 2016 National Health Interview Survey found that high-impact chronic pain and chronic pain that does not limit major life activities were linked to various physical and mental conditions.
Scientists from the University of Eastern Finland have identified alterations occurring in the human brain that signal the early stages of this common neurogenerative disease.